📋 Tender Overview
Chemosensation In Holothruoids
Chemosensation Is A Critical Signalling Process For Sea Cucumbers Which Relies On The Interaction Between Their Chemosensory Receptors And Various Ligands For Foraging And Reproduction. Although There Is A Vast Amount Of Research On The Chemistry Of Secreted Specialized Metabolites Of Sea Cucumbers, And Some Behavioural Data Evidencing Chemoreception Of These Metabolites, The Chemosensory Receptors Of These Organisms Have Not Yet Been Identified And Nothing Is Known About The Physiology Behind Sea Cucumber Chemosensation. This Setback Is In Large Part Because The Scientific Approach Behind Studying Chemosensation Requires A Vast Array Of Techniques And Expertise In Ethology, Chemistry, Molecular Biology, And Biophysics.
Firstly, A Behaviour Associated With A Chemical Cue Must Be Quantifiable, Secondly, The Precise Chemical Cue Eliciting The Behaviour Response Must Be Identified And Isolated, Thirdly, The Chemosensory Receptor Of This Specific Cue Needs To Be Identified On A Tissue, Cellular, And Molecular Level, And Finally, The Activation Of This Specific Receptor By A Specific Chemical Cue Must Elicit A Measurable Response On A Molecular, Cellular, Tissue, And Organismal Level.
Through This Project, I Will Elucidate The Physiology Of Chemical Communication Between Sea Cucumber By Considering These Sequential Steps In Chemosensation. With My Previous Experience In Sea Cucumber Ethology And Chemistry, Sensholo Will Enrich My Skill Base In Molecular Biology And Biophysics So That The Mechanisms Behind Intraspecific Chemical Communication Between Sea Cucumbers May Be Determined From Both The Emitter And Receiver Perspective; From Signal To Receptor.
This Holistic Approach Will Be Ground-Breaking In Chemosensation And Sea Cucumber Research. It Will Enable Future Research To Address The Evolution Of Chemosensation In Marine Invertebrates And The Chemical Ecology Of Sea Cucumbers Both In The Context Of Optimizing Aquaculture And In Their Ecological Conservation.
Funded Under
Marie Sklodowska-Curie Actions (Msca)
Total Cost
€ 0,00
Eu Contribution
€ 226 751,04
Coordinated By
Universitetet I Bergen
Norway
Start Date
1 September 2025
End Date
31 August 2027
Objective
Chemosensation is a critical signalling process for sea cucumbers which relies on the interaction between their chemosensory receptors and various ligands for foraging and reproduction. Although there is a vast amount of research on the chemistry of secreted specialized metabolites of sea cucumbers, and some behavioural data evidencing chemoreception of these metabolites, the chemosensory receptors of these organisms have not yet been identified and nothing is known about the physiology behind sea cucumber chemosensation. This setback is in large part because the scientific approach behind studying chemosensation requires a vast array of techniques and expertise in ethology, chemistry, molecular biology, and biophysics.
Firstly, a behavio
